PHYTOCHEMICAL STUDY, ANTIFUNGAL ACTIVITY TEST OF METHANOL EXTRACT OF QUININE LEAVES (Chinchona officinalis L)

Abstract

This study aims to determine the quality characteristics and phytochemical screening of Simplisia performed on quinine leaves simplisia and the methanol extract of leaves. Extraction was done by maceration with methanol. Furthermore, antifungal activity test for Candida albicans is done to
the extracts to determine how much the minimum inhibitory concentration. The result of the research indicated that the simplisia quality characteristics and phytochemical screening results showed positive results contain alkaloids, flavonoids, steroids / triterponoid and quinones and antifungal activities to Candida albicans which is indicated by the results of MIC compared by nystatin standard. In conclusion, the methanol extract of the quinine leaves have
antifungal activity against Candida albicans.

Keywords: Quinine leaves (Cinchona officinalis L), Phytochemycal Study, Antifungal Activity Test