ANALISIS EFEKTIVITAS BIAYA KOMBINASI OBAT ANTIHIPERTENSI PADA PASIEN RAWAT INAP DI RSUD Dr. SOEKARDJO TASIKMALAYA
DOI:
https://doi.org/10.36465/jop.v2i1.472Abstract
Hypertension is still being a health problem in the world. The blood pressure of most patients with hypertension are not controlled with single therapy meanwhile the medical costs are increasing annually, so that it needs to analyzed the cost effectiveness treatment to find out the most cost effective and provide the best outcome of therapy. This research aim to know the most effective antihypertensive two combination therapy in hospitalization RSUD dr. Soekardjo Tasikmalaya on 2017. This is a descriptive research that using pharmacoeconomic consideration with Cost Effectiveness Analysis method based on hospital perspective. This research using retrospective data of hypertension patient in hospitalization RSUD dr. Soekardjo Tasikmalaya during 2017 and sample who met the inclusion criteria were 35 patients. The data of study are categorized by kind of therapy and analyzed to get cost effective therapy for any category. The result showed that antihypertensive combinations are combination two, three and also four drugs. Cost effective treatment for any category are ACE-I-Diuretic for combination two drugs antihypertensive, ACE-I-β-Blocker-CCB for combination three drugs antihypertensive and ACE-Ia-ACE-Ib-CCB-Diuretic for combination three drugs antihypertensive. The lowest ICER Rp. 12.511,02 is shown between therapy combination ACE-I-CCB-Diuretic and ACE-I-ARB-Diuretic.
Keywords: Cost Effectiveness Analysis, combination antihypertensive, hospitalization.
References
Andayani, T.M., 2013, Farmakoekonomi Prinsip dan Metodologi, Bursa Ilmu, Yogyakarta, hal 3-16, 73-89.
Bell, K., Twiggs, J., Olin, B.R., 2015, Hypertension: The Sillent Killer Updated JNC 8 Guideline Recommendations, Alabama Pharmacy Association, Alabama
Chobanian, A.V., Bakris, G.L., Black , H.R., Chusman, W.L., Green I.A., Izzo, J.L, Jones, D.W., Materson, B.J., Oparil, S, Wrihat, J.T, 2003, JNC VII Express: The Seventh Report of the Joint National Commite on Preventian, Detection, Evaluation and Treatment of High Blood Presure, U.S. Deparment of Health and Human Services, pp 1-12.
Dewi, F.S.P., 2016, Profil Penggunaan Obat Hipertensi di Rawat Jalan RSUD dr. Soekardjo Kota Tasikmalaya Periode Januari-Desember 2015, Karya Tulis Ilmiah, Program Studi D III Farmasi Jurusan Farmasi Poltekkes Kemenkes Tasikmalaya, Tasikmalaya.
Kemenkes R.I.a, 2013, Riset Kesehatan Dasar, Kementerian Kesehatan Republik Indonesia, Jakarta, hal 88-89.
Kemenkes R.I.b, 2013, Infodatin Hipertensi, Kementerian Kesehatan Republik Indonesia, Jakarta.
Nafrialdi., 2007, Antihipertensi, dalam Gunawan, S.G., Setiabudy, R., Nafrialdi., Elysabeth, Farmakologi dan Terapi, Edisi 5, EGC, Jakarta, hal 341-360.
Rustiani, E., Andrajati, R., dan Arsyanti, L., 2014, Analisis Penggunaan Obat Antihipertensi di Poliklinik Rawat Jalan Rumah Sakit PMI Bogor: Perbandingan Cost Effectiveness dan Kualitas Hidup Pasien, Jurnal Ilmu Kefarmasian Indonesia, Vol. 12 No. 2, hal 209-215.
Suprapti, B., Nilamsari, W.P., Hapsari, P.P., Muzayana, H.A., Firdausi, H., 2014, Permasalahan Terkait Obat Antihipertensi pada Pasien Usia Lanjut di Poli Getriatri RSUD dr. Soetomo Surabaya, Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, Vol. 1 No. 2, hal 26-41.
Timur, W.W., Andayani, T.M., Aribawa, R., 2007, Analisis Efektivitas Biaya Kombinasi Antihipertensi Oral Pasien Hipertensi Rawat Jalan di Rumah Sakit Umum Daerah Tugurejo Semarang Periode 2007, Jurnal Of Medicine And Health Sains Medika, Vol. 4 No. 2, hal 124-133.
Yogiantoro, M., 2010, Hipertensi Esensial, dalam Sudoyo, A.W., Setiyohadi, B., Alwi, I., Simadibrata, M., Setiati, S., Ilmu Penyakit Dalam, Edisi 5 Jilid 1, Penerbit FK UI, Jakarta, hal 1082-1084.
