Molecular Binding of Quarcetin Compounds on B-Cell Lymphoma 2 (4AQ3) Receptors as Cervical Cancer

Abstract

Cervical cancer is a cancer caused by oncogenic human papilloma virus (HPV), which attacks the uterine wall. Based on WHO data as many as 490,000 in the world every year every woman is diagnosed with cervical cancer. The aim of this study was to tether the quarcetin compound molecule to the B-Cell Lymphoma 2 (4AQ3) receptor as cervical cancer. The results obtained from the experiment are the validation of the receptor docking method that has been validated (X = -20,839, Y = 7.21 and Z = -9.584). In this study, quarcetin compounds were less stable and less effective at Bcl-2 receptors than natural ligands