Formulasi Sediaan Hand and Body Lotion Ekstrak Metanol Buah Paprika Merah (Capsicum annuum Linnaeus) sebagai Antioksida
Abstrak
Red bell pepper (Capsicum annum L.) contains various types of carotenoid compounds that have the potential as antioxidants. The methanolic extract of red bell pepper fruit has been previously investigated as an antioxidant. Peppers are special compared to other chilies, because they contain very high vitamin C. Red bell pepper is one of the fruits with the main compound content is carotenoids which act as antioxidants. Objective: The purpose of this study was to formulate the preparation of hand and body lotion extra methanol from red bell pepper (Capsicum annum L.) and to determine the effect of differences in the concentration of methanol extract of red bell pepper (Capsicum annum L.) in the preparation of hand and body lotion which is effective as a skin moisturizer. Methods: This study used an experimental method. namely the thick extract of red bell peppers obtained by extracting by maceration in the preparation of hand and body lotion which is effective as a skin moisturizer. Several hand and body lotion formulas have been made containing methanol extract of red bell pepper (Capsicum annum L.) by varying the extract, namely 1%, 5%, and 7.5%. To determine the antioxidant activity was determined by the free radical scavenging test DPPH (1,1-diphenyl-2-picrihydrazil). Results: The results of this study indicate that all hand and body lotion formulas have met the evaluation parameters of hand and body lotion while the results of the antioxidant activity test each formula F1 (278.025±0.405), F2 (132.737± 1.347) and F3 (79.816± 2.551) ppm. Conclusion: Based on antioxidant testing, the best preparation found in formula 3 has a strong antioxidant content.Referensi
Amrun, dan Umiyah. 2005. Pengujian
Antiradikal Bebas Difenilpikril Hidrazil
(DPPH) Ekstrak Buah Kenitu
(Chrysophyllum cainito L.) dari Daerah
Sekitar Jember, dalam Jurnal ILMU
DASAR, Vol.6 No. 2 : 110-114.
Haerani, Ani, Anis Yohana Chaerunisa, Anas
Subarnas. 2018. ANTIOKSIDAN
UNTUK KULIT. Farmaka, 16 (2):135–
Megantara INAP, Megayanti K, Wirayanti R,
Esa IBD, Wijayanti NPAD, Yustiantara
PS. 2017. Formulasi Lotion Ekstrak
Buah Raspberry (Rubus rosifolius)
Dengan Variasi Konsentrasi
Trietanolamin Sebagai Emulgator Serta
Uji Hedonik Terhadap Lotion. Jurnal
Farmasi Udayana, 6(1): 1–5.
Molyneux, P., 2004. The Use of The Stable
Free Radical Diphenylpicryl-hydrazyl
(DPPH) for Estimating Antioxidant
Activity, Songklanakarin J. Sci.
Technol. 26(2): 211-21
Nurmillah, O. Y. 2009. Kajian aktivitas
antioksidan dan antimikroba ekstrak
biji, kulit buah, batang dan daun
tanaman jarak pagar (jatropha curcas
L.). (Skripsi), Institut Teknologi
Bandung, Bogor
Panjaitan, T. D., Prasetyo, B., Limantara, L.,
, Peranan Karotenoid Alami dalam
Menangkap Radikal Bebas, hal 79-86,
Universitas Ma Chung, Malang.
Rowe RC, Sheskey PJ, Owen SC, Handbook
of pharmaceutical Exipients, 6nd
Edition, London : Pharmaceutical
Press, 2009
Warsi dan Guntarti, A., 2013, Aktivitas
Antioksidan Ekstrak Metanol Paprika
Hijau (Capsicum annuum, L.) dengan
Metode Penangkapan Radikal DPPH,
Jurnal Ilmiah Kefarmasian,
Pharmaciana, 3 (1) : 9-19.
Warsi dan Guntarti, A., 2017. Aktivitas
Antioksidan Ekstrak Metanol Paprika
Kuning (Capsicum annuum, L.) dengan
Metode Penangkapan Radikal DPPH,
Pharmaciana, 7 (2) : 123-132