OPTIMASI FORMULA SABUN CAIR EKSTRAK ETANOL 96% DAUN BANDOTAN (Ageratum conyzoides L.) DENGAN METODE DESAIN FAKTORIAL

M. Andi Chandra, Willsaning Diniyanti, M. Hidayatullah Hidayatullah

Abstract


The skin is the outermost part of the body that is susceptible to bacterial infection. Therefore the skin requires a preparation that effectively kills bacteria such as liquid soap. Bandotan leaves are plants that have been known to contain antibacterial properties. The physical properties of liquid soap are affected by the HPMC and castor oil used. The purpose of this study was to determine the effect of varying the concentration of HPMC and castor oil needed on the characteristics of the 96% ethanol extract liquid soap formula of Bandotan leaves (Ageratum conyzoides L) and to determine the optimal composition of castor oil and HPMC in the optimum formula for 96% ethanol extract liquid soap. Bandotan leaves (Ageratum conyzoides L) using a factorial design method. This study used bandotan leaf extract, which was prepared by maceration extraction method using 96% ethanol solvent. Statistical test results obtained <0.05, namely 0.004 for PH, 0.035 foaming power and 0.045 Viscosity, so it can be concluded that variations in the concentration of HPMC and castor oil affect the characteristics of the liquid soap formula with 96% ethanol extract of bandotan leaves.

 


Full Text:

PDF (Indonesian)

References


Almira J, Yusransyah, Banu K, Rahmawida Pu, Nuriyatul F. 2021. Aktivitas Antibakteri Ekstrak Etanol Daun Bnadotan (Ageratum conyzoides) Terhadap Bakteri Staphylococcus Pyogenes. Jurnal of pharmaceutical and helath research.

Ardina, A., dan Suprianto, S. 2017. Formulasi Sabun Cair Antiseptik Ekstrak Etanol Daun Seledri (Apium gramaveolens L). Jurnal Dunia Farmasi 2 (1), 21-28.

Ance, P. E., Wijaya, S., & Setiawan, H. K. (2018). Standarisasi dari daun kirinyuh (Chromolaena odorata) dan simplisia kering dari tiga daerah yang berbeda standardization of siam weed (Chromolaena odorata) leaves and dry powder form collected from three different areas. Journal of Pharmacy Science and Practice, 5(1), 78–86.

Dimpudus, S. A., Yamlean, P. V. Y., dan Yudistira, A. 2017. Formulasi Sediaan Sabun Cair Antiseptik Ekstrak Etanol Bunga Pacar Air (Impatiens balsamina L.) dan Uji Efetivitasnya terhadap Bakteri Staphylococcus Aureus Secara in Vitro. Jurnal Ilmiah Farmasi – UNSRAT, 6(3), 208–215.

Dlova, N. C., Naicker, T., & Naidoo, P. 2017. Soaps and Cleansers For Atopic Eczema, Friends or Foes What Every South African Paediatrician Should Know About their pH. SAJCH South African Journal of Child Health. http://www.sajch.org.za/index.php/sajch/article/view/1386. Diakses pada 3/12/2022 10:00 WIB.

Laksana, K.P Oktavillariantika, A.A.I.A.S, Pratiwi N.L.PA, Wijayanti, N.P.A.D dan Yustiantara, P.S. 2017. Optimasi Konsentrasi HPMC Terhadap Mutu Fisik Sediaan Sabun Cair Menthol. Jurnal Farmasi UDAYANA Vol. 6 No.1.

Rahmawanty, D., dan Sari, D.I. 2019. Buku Ajar Teknologi Kosmetik. CV IRDH. Malang.

Raissi S dan Farzani R.E 2009. Statistical process optimization throuht multiresponse surface methodology. World academy of science, engineering and technology, pp. 267-271.

Sari AN. 2015. Antioksidan Alternatif Untuk Menangkal Bahaya Radikal Bebas Pada Kulit. Jurnal Islam Sci Technol. 1(1), 63–8.

Sudarmadji, S, dkk. 2007. Analisis Bahan Makanan dan pertanian. Liberty Yogyakarta.




DOI: http://dx.doi.org/10.36465/jop.v6i3.1198

Refbacks

  • There are currently no refbacks.


Copyright (c) 2024 M Andi Chandra

p-ISSN: 2620-8563; e-ISSN: 2621-1521


Index:

RJI Main logo